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Andrographis Paniculata - Hempedu Bumi from

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 Andrographis is used to support healthy digestive, cardiovascular and urinary systems. Andrographis paniculata contains many flavonoids, which have anti-inflammatory properties. Andrographolide, an active component of andrographis paniculata, inhibits inflammatory responses by rat neutrophils.

 

Amala Cancer Research Centre, Thrissur, Kerala, India.

In this study, we explored the antioxidant and anti-inflammatory properties of the
medicinal herb Andrographis paniculata using in vitro as well as in vivo systems.
Methanolic extract of Andrographis paniculata was found to inhibit formation of
oxygen derived free radicals such as superoxide (32%) hydroxyl radicals (80%)
lipid peroxidation (80%) and nitric oxide (42.8%) in in vitro system. In vivo
studies using BALB/c mice models also showed significant inhibition in PMA
induced superoxide (32.4%) and nitric oxide (65.3%) formation. Interestingly we
also found that, administration of Andrographis paniculata extract produced
complete inhibition of carageenan induced inflammation compared with control
models.

 
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