Paliperidone

Brand:aa

Product detail:

Paliperidone
Cas No:144598-75-4
MF:C23H27FN4O3
Use:atypical antipsychotic
Appearance:white crystalline powder

Paliperidone

 

1.General info:Paliperidone also known as 9-hydroxyrisperidone, is an atypical antipsychotic, it is an extended release formulation of paliperidone that uses the OROS extended release system to allow for once-daily dosing. paliperidone palmitate is a long-acting injectable formulation of paliperidone indicated for once-monthly injection after an initial titration period. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone (paliperidone is 9-hydroxyrisperidone, i.e. risperidone with an extra hydroxyl group). It is indicated for the acute and maintenance treatment of schizophrenia.

 

2. Pharmacology: While its specific mechanism of action is unknown, it is believed paliperidone and risperidone act via similar, if not identical, pathways; therapeutic effect may be due to a combination of D2 and 5-HT2A receptor antagonism. Paliperidone also has antagonist effect at α1 and α2 adrenergic receptors and at H1 histamine receptors. It does not bind to muscarinic acetylcholine receptors.
Paliperidone was approved by the FDA for the treatment of schizophrenia on December 20, 2006. This agent will initially be marketed for the treatment of schizophrenia and then for bipolar mania. Clinical trials of paliperidone for the treatment of schizoaffective disorder are also planned. It may also be used off-label for other conditions. Like risperidone, its possible use in people with autism and Asperger syndrome may be studied.

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Ourselves

1).10 years experience in plant extract

2). HACCP and KOSHER certificated

3). GMP factory

4). Large quantity in stock

Product characteristics

1). extracted from the natural Onion with a special process, the whole process

  Conforms to the GMP requirements strictly

2). we have gained ISO, HACCP, KOSHER, AND GMP certificate

3). water and ethanol as solvent, ensure the safety of the product

4). complete product tracing system and technical service

SECOND------ Our main products

1.Stevia extract	RA97%
2.Pomegranate extract	ellagic acid 90%
3.Onion extract powder	10:1
4.Wolfberry extract	polysaccharide 50%
5.Olive leaf extract	30% HPLC
6.Epimedium extract	icariin 10-90%
7.Amur cork-tree extract
8.Dodder seed extract	60%
9.Lemon balm extract	flavone 3-5%
10.Coix seed extract	GMP factory
11.Platycodon root extract
12.Hawthorn extract	GMP factory
13.Angelica extract
14.Smoketree extract
15.Horse chestnut extract	10-98%
16.Senna lesf extract
17.Polygonum extract	10:1
18.Banaba leaf extract	1-10%
19.Shiitake mushroom extract	polysaccharide 20%
20.Reishi extract	polysaccharide 30%

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Mr. Liu

Qingdao fraken international trading co., ltd 

Address: RM1005 post mansion yan’an three road ,qingdao ,China

Tel: 0086 532 83899718

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